Effect of overexpression of ppar on the healing process of corneal alkali burn in mice
نویسندگان
چکیده
Shizuya Saika, Osamu Yamanaka, Yuka Okada, Takeshi Miyamoto, Ai Kitano, Kathleen C. Flanders, Yoshitaka Ohnishi, Yuji Nakajima, Winston W.-Y. Kao, and Kazuo Ikeda Department of Ophthalmology, Wakayama Medical University, Wakayama, Japan; Laboratory of Cell Regulation and Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda, Maryland; Department of Anatomy, Graduate School of Medicine, Osaka City University, Abeno, Osaka, Japan; and Department of Ophthalmology, University of Cincinnati Medical Center, Cincinnati, Ohio
منابع مشابه
Effects of nicotine on corneal wound healing following acute alkali burn
Epidemiological studies have indicated that smoking is a pivotal risk factor for the progression of several chronic diseases. Nicotine, the addictive component of cigarettes, has powerful pathophysiological properties in the body. Although the effects of cigarette smoking on corneal re-epithelialization have been studied, the effects of nicotine on corneal wound healing-related neovascularizati...
متن کاملPathological Evaluation of Two Techniques of Amniotic Membrane Patching on Experimentally Induced Corneal Lesions in Dogs
Objective- This study was performed to evaluate and compare grossly and pathologically two surgical techniques of amniotic membrane patching on experimental corneal alkali burn in dogs. Design- Experimental study. Animals- Fifteen healthy dogs Procedures- The central corneas of the dogs were inflicted by applying a round filter paper, 6.0 mm in diameter, soaked in 1 N NaOH for 60 sec. ...
متن کاملEffect of overexpression of PPARgamma on the healing process of corneal alkali burn in mice.
Wound healing involves both local cells and inflammatory cells. Alkali burn of ocular surface tissue is a serious clinical problem often leading to permanent visual impairment resulting from ulceration, scarring and neovascularization during healing. Behaviors of corneal cells and inflammatory cells are orchestrated by growth factor signaling networks that have not been fully uncovered. Here we...
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Objective- To compare the effects of topical eye-drop and subconjunctival administration of diclofenac on improvement of experimental corneal alkali wound in rabbits eyes. Design- Experimental study. Animal- fifteen rabbits. Procedures- Alkali wounds were inflicted on the central corneas of 15 rabbits which we...
متن کاملInfluences of combining nano zinc, honey and Aloe vera to accelerate healing the wounds caused by third–degree burn in male balb/c mice
Introduction: Burns are one of the most common household and industrial injuries. There are evidences which demonstrate the therapeutic properties of honey and Aloe vera. We evaluated the topical influences of this material and nano zinc combination on healing the wounds caused by third-degree burns. Materials and methods: 32 balb/c mice divided into a control group (without treatment), grou...
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تاریخ انتشار 2007